Hidradenitis suppurativa is a chronic dermatological condition characterized by inflamed, swollen lumps that are typically painful and may rupture, releasing fluid or pus. The areas most commonly affected are the underarms, under the breasts, and the groin. Scar tissue remains after healing.
The exact cause is usually unclear, but it is believed to involve a combination of genetic and environmental factors. About one‑third of people with the disease have an affected family member. Other risk factors include obesity and smoking. The condition is not caused by infection or poor hygiene.
No cure is known. Incising the lesions to allow drainage provides little benefit. Although antibiotics are commonly prescribed, the supporting evidence is weak. Immunosuppressive medications may also be tried. In more severe disease, laser therapy or surgery to remove the affected skin may be viable. Rarely, a skin lesion can develop into skin cancer.
When mild cases are included, the estimated prevalence is 1–4 % of the population. Women are three times more likely to be diagnosed than men. Onset is typically in young adulthood.
Hidradenitis suppurativa is a long-term dermatological condition characterized by the occurrence of inflamed and swollen lumps. These are typically painful and break open, releasing fluid or pus. The areas most commonly affected are the underarms, under the breasts, and the groin. Scar tissue remains after healing.
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Hidradenitis suppurativa (stage I) in the armpit. This is a very mild case of Hidradenitis suppurativa.
Hidradenitis suppurativa Stage III
Hidradenitis suppurativa Stage III ― Inflamed lesion.
Hidradenitis suppurativa Stage III ― Open lesions are extremely painful.
Hidradenitis suppurativa is a chronic, recurrent, and debilitating skin condition. It is an inflammatory disorder of the follicular epithelium, but secondary bacterial infection can often occur. The diagnosis is made clinically based on typical lesions (nodules, abscesses, sinus tracts), locations (skin folds), and nature of relapses and chronicity.
Non-biologic and non-procedural treatments are often used as monotherapy for mild disease and can be used in conjunction with biologic therapy and surgery for moderate to severe disease. Recent studies highlighted in this review add support for the use of intralesional corticosteroids for HS flares and localized lesions, and there is evidence that monotherapy with tetracyclines may be as effective as the clindamycin/rifampicin combination.
Many treatments are used for hidradenitis suppurativa, including antibiotics, retinoids, antiandrogens, immune-suppressing drugs, anti-inflammatory medications, and radiotherapy for early lesions. The top recommended treatments are adalimumab and laser therapy. Surgery, either simple excision or complete local excision with skin grafting, is the preferred option for severe, advanced cases that don't respond well to other treatments.
The exact cause is usually unclear, but it is believed to involve a combination of genetic and environmental factors. About one‑third of people with the disease have an affected family member. Other risk factors include obesity and smoking. The condition is not caused by infection or poor hygiene.
No cure is known. Incising the lesions to allow drainage provides little benefit. Although antibiotics are commonly prescribed, the supporting evidence is weak. Immunosuppressive medications may also be tried. In more severe disease, laser therapy or surgery to remove the affected skin may be viable. Rarely, a skin lesion can develop into skin cancer.
When mild cases are included, the estimated prevalence is 1–4 % of the population. Women are three times more likely to be diagnosed than men. Onset is typically in young adulthood.